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Treatment

Treatment and Risks of Radiofrequency ablation | Oncology

What is radiofrequency ablation?

Radiofrequency ablation, also known as a rhizotomy, is a minimally invasive, non-surgical procedure that uses heat to reduce or stop the transmission of pain. Radiofrequency waves kill or burn a nerve that causes pain, especially the transmission of pain signals to the brain.

Radiofrequency ablation uses an electrical current to heat a small area of ​​nerve tissue and stop sending pain signals. Provides permanent relief to those with chronic pain, especially in the back, neck, and arthritic joints. This procedure is commonly used to treat chronic pain and spinal conditions such as arthritis (spondylosis) and sacroiliitis.

It is also used to treat pain in the neck, back, knee, pelvis, and peripheral nerves. Advantages of radiofrequency ablation: Avoidance of surgery, immediate pain relief, reduced recovery time, reduced need for pain relievers, better performance, and faster return to work and other activities.

Who is the candidate?

Diagnosis Radiofrequency ablation is a treatment option for patients who have experienced successful pain relief after injection of nerve/pain receptor blockade.

Radiofrequency ablation is done under fluoroscopic guidance (X-rays) and should not be done in people with infection, pregnancy, or bleeding problems.

What are the risks?

The risk of complications from radiofrequency ablation is very low. Serious complications, including infection and bleeding at the incision site, are rare.

Temporary side effects include:

  • Weakness or numbness in the legs
  • Swelling and bruising at the incision site

How is radiofrequency ablation performed?

First, you will be given medications through an IV to help you relax. Then you will fall face down or on your back on the x-ray table. The doctor will numb your skin area with a local anesthetic. So he or she inserts a fine needle into the area where you feel pain. X-rays can help your doctor identify the exact area

Insert the microelectrode through the needle. Ask your doctor if you feel tingling. This will help your doctor identify the correct area for treatment. Sends a small radiofrequency current through the electrode to heat the nerve tissue. You can usually go home the same day after the procedure.

How effective is radiofrequency ablation?

Most patients experience some pain relief after radiofrequency ablation, but this amount varies with pain and position. Relief lasts six to 12 months. For some patients, the relief lasts for years.

What happens before treatment?

The doctor performing this procedure will review your medical history and previous imaging studies to plan the best site for the ablation. Be prepared to ask yourself any questions you may have at this appointment. Patients taking aspirin or blood thinners should stop taking it several days before the procedure.

Discuss any medications with your doctor, including the person prescribing the medicine and the doctor who gave the injection. The procedure is usually performed in a special procedure room for patients with access to fluoroscopy. Arrange for someone to drive you to the office or patient center on the day of the abortion.

What happens during treatment?

During the process, you will be asked to sign consent forms, list the medications you are currently taking and if you have any drug allergies. The short procedure can take at least 15 to 45 minutes, followed by a recovery period.

Step 1: Prepare the patient

The patient lay on the x-ray table. Local anesthesia is used to numb the treated area. The patient experiences minimal discomfort throughout the procedure. The patient is alert and aware of the feedback process to the physician. Low-dose sedatives like valium or versed are usually the only medications given for this procedure.

Step 2: Insert the needle

The nerve ablation technique is similar to that used for diagnostic blocks. With the help of a fluoroscope (special X-ray), the doctor will insert a thin, hollow needle into the area causing the pain. Fluoroscopy allows the doctor to view the needle in real-time on a fluoroscopic monitor to see where the needle is going. Contrast can be injected to ensure correct needle position. Some discomfort may occur, but patients often experience more stress than pain.

Step 3: Deliver the heating flow

Once the needle is in place, the patient suffers from cramps. Next, a small, precise burn the size of the tip of a cotton swab sends a radiofrequency current through a hollow needle called a wound. The current destroys the part of the nerve that transmits pain and interferes with the signal that produces pain. The burn takes about 90 seconds at each site and can burn multiple nerves at the same time.

What happens after the treatment?

Most patients return immediately after the procedure. After supervising for a while, you can usually leave the office or suite. Someone has to take you home. Patients may experience pain for up to 14 days from this procedure, but this is usually caused by the residual effects of nerve ablation or muscle spasm. Patients typically go up and down 24 to 72 hours after the procedure.

Pain relief is generally experienced within 10 days, although in some patients relief may be immediate and in others, it may take up to three weeks. Patients should schedule a follow-up appointment with the prescribing physician to document efficacy and post-procedure to address any issues with the patient for future treatments and evaluations.

Recovery

After the procedure, you may develop sores in the destination area for a few days. Rare complications include infection, bleeding, and nerve damage. Pain relief lasts from 9 months to more than 2 years. There is the possibility of nerve regeneration through a burn created by radiofrequency ablation. If the nerve grows back, it will take 6 to 12 months after the procedure.

Radiofrequency ablation is effective in those with 70-80% successful nerve blocks. This procedure can be repeated if necessary. Although results vary from patient to patient, the effect of ARF lasts from 3 to 12 months. Oftentimes, the nerve eventually regenerates, and in some cases, joint pain can return.

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Equipment

Plastic Surgery Equipment Cost and Post Surgery | Dermatology

What is plastic surgery?

Before getting the details regarding plastic surgery equipment, first of all, know about the Plastic surgery. Plastic surgery is the repair, reconstruction, or alteration of the body through surgical treatments. These are for cosmetic purposes, whether it’s to alter the body or recover from physical trauma.

Most likely, you have seen the results of the work of plastic surgeons many times. And you might not even think about what normally stands behind a surgeon’s high professionalism. An excellent professional is required to have in-depth medical knowledge, many hours of practice, and continuous professional development.

Any patient will utilize the administrations of an accomplished specialist unafraid. However, there is another integral part of a successful surgery – high-quality tools.

Compare and reduce cost over these other plastic surgery equipment used in:

  • Plastic surgery procedures are performed to restore, alter, replace, or reconstruct areas of the body in areas such as skin, cranio, and maxillofacial, musculoskeletal, hand, breast, and torso.
  • Types of plastic surgery equipment commonly used in plastic surgery include:
    • Awls, chisels, curettes, gouges, and mallets
    • Pliers, osteotomes, rasps, rongeurs, and wire and pin instruments
    • Electrosurgical instruments, for example, bipolar and monopolar forceps, cables, and electrosurgical units
    • Cannulas, calipers, gauges, markers, and rulers
    • Clamps, forceps, graspers, elevators, and spreaders
    • Dissectors, elevators, hooks, and probes
    • Endo brow lift instruments, knives, and punches
    • Needle holders and needles
    • Speculums and retractors in styles such as hand-held, self-retaining, and fiberoptic
    • scissors in traditional and super-cut style

Here is the information regarding plastic surgery equipment and characteristics that have the plastic surgery equipment which is used while performing the plastic surgery and also the plastic surgery equipment which is used in different steps while doing the plastic surgery.

Medical supplies for plastic surgery from the manufacturer

Nowadays, talented plastic surgeons have become real celebrities in the USA and Europe. Many famous actors and models stand in line to get a date with them. However, only colleagues can understand the difficulties and challenges that surgeons face every day. To provide their patients with the expected results and safety, high-quality surgical instruments are one of the non-negotiable requirements.

  • Durability and strength of assembly parts: To focus completely on the work process, you must ensure the quality of every detail.
  • Ergonomics: The surgery can take several hours. Hence, it is important that the tool is light and comfortable to use. All new med products are effective and easy to use.
  • Wear-resistant: Sterility is an absolute rule in the surgical room and no compromises are allowed in it, repeated sterilization can shorten the life of the instruments. We have solved this problem, and now you can save a significant portion of your plastic surgery clinic budget. In the New Med plastic surgery instruments category, you will find high-quality instruments for plastic surgeons.
  • Anesthesiology equipment: The anesthesia equipment at Medical includes all the tools necessary to safely manage anesthesia during surgical procedures, including plastic surgery. Doctors have access to reliable anesthesia machines, including certified pre-owned models that have been refurbished to excellent condition.

Liposuction aspirators for plastic surgery

Liposuction is a surgical procedure to remove excess fat from parts of the body through suction. Doctors will find a variety of aspiration and assembly equipment available from trusted brands. Straws and tubes can be used to safely remove excess fat, and collected in glass or plastic containers before disposal.

Fat grafting system for plastic surgery

Fat grafting is the process of removing and transferring excess fat from areas of the body to other areas of the body. This procedure is popular for liposuction and breast treatment, and it is considered best for patients, as they use their own tissues for the procedures.

The equipment needed to perform fat injection procedures, including syringes, shelves, snap syringe locks, injection guns, and cannula.

Endoscopy equipment for plastic surgery

Endoscopy equipment is any small and thin recording device used to look inside the body. It is usually inserted through an open cavity, such as the throat or nose, to obtain an internal view of an organ or other open area of the body. Endoscopy is not a treatment or a surgical procedure, but rather a monitoring tool for doctors to obtain an accurate picture of a patient’s condition. From there, they can better evaluate and create a treatment plan with the patient.

Surgery lights and tables

Any plastic surgeon needs reliable and bright lighting to better treat their patients and complete the procedures with plastic surgery equipment. Various lighting options from Burton, which are available in three mounting styles: wall mount, ceiling mount, or floor mount. These surgical lights can be easily adjusted with one hand, shaping them in such a way that shadows do not block the light.

Post-surgery compression garments

Compression garments can be considered one of the most important tools in a patient’s recovery from plastic surgery. They continue to restore stable, orderly, and shaped areas of the body so that the body part heals properly. Includes available compression garments:

  • Abdominal binders
  • Torso garments
  • Compression vests
  • Facial wraps / Garments
  • Arm and back garments
  • Compression bra / Breast augmentation wraps / Mammary supports
  • Above knee compression girdles
  • Compression belts
Categories
Treatment

Preparation and Risk Factors of Cryoablation | Oncology

What is cryoablation?

Cryoablation for cancer is a treatment to kill cancer cells with a severe cold. During cryoablation, a thin wand-shaped needle (cryoprobe) is inserted through the skin and directly into the cancerous tumor. Gas is sent to the cryoprobe to freeze the tissue. The tissue is then allowed to thaw. The freezing and thawing process is repeated several times in a single treatment session. This is used for cancer when surgery is not an option.

Cryoablation is sometimes used as the primary treatment to:

  • Bone cancer
  • Cervical cancer
  • Eye cancer
  • Kidney cancer
  • Liver cancer
  • Lung cancer
  • Prostate cancer

This is also used to relieve pain and other symptoms caused by bone (bone metastasis) or cancer that has spread to other organs. Cryoablation for cancer is also known as percutaneous cryoablation, cryosurgery, or cryotherapy.

Risks factors of cryoablation

It is a safe process with many benefits. More importantly, treatment has been very successful in stopping the growth or spread of cancer cells. It provides patients with a faster recovery time with less pain compared to surgical treatment of the tumor.

As with all medical procedures, it carries some minor risks, such as bleeding, infection, and accidental damage to nearby healthy organs. Advanced imaging guidance can help your care team minimize these risks as much as possible.

How to prepare for cryoablation

Before your procedure, your interventional radiologist will ask about your current medications, as some may need to be stopped prior to the scheduled procedure, including blood thinning. Blood tests may also be ordered to make sure your immune system responds and is able to clot.

Your care team will inform you of any restrictions on what you can eat and drink before your appointment. Since you will receive anesthesia during cryoablation, be sure to travel home.

Why cryoablation happens

It is a well-tolerated treatment for a variety of cancers, including:

  • Bone
  • Cervical
  • Eye
  • Liver
  • Lung
  • Kidney
  • Prostate

This can be used to reduce pain and other symptoms caused by the spread of cancer. It is generally recommended when the patient is unable to surgically remove the tumor due to age, general disease burden, or problems with the patient’s heart or lung function.

Cryoablation may be the only method to reduce cancer symptoms when the mass is too dangerous to function, or it may be part of a larger multi-treatment treatment plan. The main characteristics of the tumor, including size, staging, and site, will help your doctor determine if it is effective in killing malignant cells.

What to expect during cryoablation

This is performed by an interventional radiologist in a patient’s setting. However, depending on the site or organ of the tumor, you may need to stay overnight after this procedure. Before the procedure begins, you may receive general anesthesia or anesthesia through an intravenous (IV) line, which will make you feel comfortable and safe during the procedure.

A local anesthetic is then applied to the area of ​​the skin that is accessed through a small incision. Your doctor will then guide a small needle through the incision using ultrasound or CT to help ensure access to the tumor mass. Once in the tumor, the cold tip of the needle freezes the tumor tissue.

Once the tumor has dissolved, the process is repeated several times during a single treatment. Once the procedure is complete, the needle is removed and the area is bandaged. From here you can go to a special recovery area or join a hospital for the night.

What happens after cryoablation? 

Full recovery from cryoablation generally takes two to three weeks, during which time patients are asked to steer clear of physically drastic measures to avoid complications after surgery. It’s a good idea to make sure you have extra help around the house at this time.

Cryoablation patients are followed by a series of MRI scans at 1, 3, and 6 months, as well as a CT-controlled needle biopsy at 6 months.

What are the benefits of cryoablation?

Conventional surgery for tumor removal requires an incision of at least 10 to 12 inches. The minimally invasive cryoablation technique requires three to four small incisions for the surgical instruments.

Cryoablation patients benefit from:

  • Reduced hospital stay (one day) and faster healing
  • Postoperative pain and need for analgesics are minimal
  • Shorter recovery time
  • Quick return to normal activity (about a week) and work (about two weeks)
  • Small incisions and fewer scars
Categories
Treatment

Cost and Side Effects of Targeted Therapy | Oncology

What is targeted therapy?

Targeted therapy is a cancer treatment that uses drugs to target exact genes and proteins that are difficult in the development and survival of cancer cells. Targeted therapy can affect the tissue environment that helps cancer grow and survive, or it can target cells related to cancer growth, such as cells in blood vessels.

Doctors often use targeted therapy sideways with chemotherapy and other treatments. The US Food and Drug Administration (FDA) has accepted targeted therapies for many types of cancers. Research is also being done to find new targeted therapy treatments.

How does targeted therapy work?

There are numerous types of cells that make up every tissue in your body. For example, there are blood cells, brain cells, and skin cells. Each guy has his own job. Cancer begins when certain genes in healthy cells change and become abnormal over time. This change is called a genetic mutation.

Genes tell cells how to make proteins to keep the cell going. If genes mutate, these proteins also change. This can cause cells to divide too much or too fast and allow cells to live much longer than normal. When this happens, cells grow out of control and form a tumor. Learn more about the genetics of cancer.

To grow targeted therapies, researchers first identify the genetic variations that help a tumor grow and change. A potential target for this therapy would be a protein that is present in cancer cells but not in healthy cells. This may be due to a mutation. Once researchers have recognized a mutation, they develop a treatment that aims for that specific mutation.

Targeted therapies can do different things to the cancer cells that they target:

  • Block or turn off the indications that tell cancer cells to grow and divide
  • Prevent cells from living longer than normal
  • Destroys cancer cells

To match the best-targeted therapy for your tumor, your doctor may order tests to learn the genes, proteins, and other factors that are unique to your tumor. This helps to find the most effective treatment. Like other treatments, embattled therapies can cause side effects and be expensive, so your doctor will try to compete for your tumor with the best possible treatment.

There are types of targeted therapies available

Many different targeted therapies have been approved for use in treating cancer. These therapies contain hormonal therapies, signal transduction inhibitors, gene look modulators, apoptosis inducers, angiogenesis inhibitors, immunotherapies, and toxin-releasing molecules.

Hormonal therapies: It slow or stop the development of hormone-sensitive tumors, which require certain hormones to grow. Hormone therapies work by preventing the body from producing hormones or by interfering with the action of hormones. Hormonal therapies have been approved for both breast and prostate cancer.

Signal transduction inhibitors: They block the activities of molecules that participate in signal transduction, the process by which a cell replies to signals from its situation. During this process, once a cell has received a specific signal, the signal is transmitted within the cell through a series of biochemical reactions that ultimately produce the appropriate responses.

In some cancers, malignant cells are stimulated to continually divide without external growth factors prompting them to do so. Inhibitors of signal transduction interfere with this inappropriate signaling.

Modulators of gene: Modulators of gene expression modifies the function of proteins that play a role in the control of gene expression.

Apoptosis inducers: It causes cancer cells to undergo a controlled cell death process called apoptosis. Apoptosis is a method the body uses to get rid of abnormal or unnecessary cells, but cancer cells have strategies to prevent apoptosis. Inducers of apoptosis can circumvent these strategies to cause cancer cell death.

Angiogenesis inhibitors:  Angiogenesis inhibitors block the growth of new blood vessels into tumors. The blood supply is essential for tumors to grow beyond a certain size because blood provides the oxygen and nutrients that tumors need for sustained growth. Treatments that delay angiogenesis can chunk tumor growth.

Some targeted therapies that inhibit angiogenesis interfere with the action of Vascular Endothelial Growth Factor (VEGF), a substance that stimulates the formation of new blood vessels. Other angiogenesis inhibitors target other molecules that stimulate the growth of new blood vessels.

Immunotherapies: It causes the immune system to destroy cancer cells. Some immunotherapies are monoclonal antibodies that recognize exact molecules on the surface of cancer cells. The binding of the monoclonal antibody to the target molecule results in the immune killing of cells expressing that target molecule. Other monoclonal antibodies bind to sure immune cells to help these cells better kill cancer cells.

Toxic molecules: Monoclonal antibodies that release toxic molecules can specifically cause cancer cell death. Once the antibody has bound to its target cell, the toxic molecule that is certain to the antibody, such as radioactive material or poisonous chemical, is taken up by the cell and ultimately kills that cell. The toxin will not affect cells that lack the target for the antibody, that is, the vast majority of cells in the body.

Why could you have targeted drug therapy?

Targeted drugs are not suitable for all types of cancer. But they are one of the main treatments for some types of cancers. For example, advanced melanoma and some types of leukemia. For some other cancers, anticancer drugs have been targeted in combination with other treatments, such as surgery, chemotherapy, or radiation therapy. Researchers are also looking for targeted drugs in clinical trials for some types of cancer.

Whether you have targeted therapy depends on:

  • The types of cancer you have
  • How far your cancer has spread (stage)
  • Other cancer treatments you’ve had

Side effects in targeted therapy

Targeted therapies can cause serious side effects. The most common are diarrhea, liver problems such as hepatitis, and changes in the skin, hair, and nails.

  • Skin problems are the hardest to treat for most people. They occur because targeted cancer therapies target the same growth factors and blood vessels that you need for healthy skin.
  • A rash that looks like acne on the scalp, face, neck, chest, and back. It can sting, burn, or hurt. Sometimes it can get infected. It usually lasts as long as you receive treatment, but goes away after treatment is finished.
  • Feeling like you have a bad sunburn. This can start before you even see changes in your skin.
  • Extreme sensitivity to sunlight.
  • Dry Skin. Almost everyone who receives targeted therapy has it. Your skin can crack, especially on your hands and feet, making it difficult to use your hands or walk.
  • Painful, swollen sores on the fingernails and toenails.
  • Sores on the scalp and hair loss or baldness. Your hair may turn a strange color or not grow back after treatment.
  • Your eyelids may be red, puffy, and turned inward or downward. This could damage the clear layer in front of the eye called the cornea.

Before starting treatment, switch to mild, chemical- and fragrance-free soaps and shampoos. Report any skin changes to your doctor immediately. You should treat them so you don’t get an infection. If the skin changes are severe, you may need to stop specific medications.

Targeted therapies can cause other side effects. Some are life-threatening. Many targeted therapies work best when combined with other treatments like chemotherapy and radiation, so you could be dealing with those side effects, too. Your doctor can explain what to expect from your treatment plan.

Cost for targeted therapy

Targeted therapies can cost 10,000 dollars a month. One type of immunotherapy, called CAR T, can be around half a million dollars. Still, the price can vary based on the type of drug, how it’s given, where you get it, and how long you take it.

For example, you will likely pay more out of pocket for pills than for treatment you receive intravenously in a hospital or clinic. Before starting any type of cancer treatment, be sure to find out what your insurance will pay for.

What to expect

There are dozens of targeted therapy drugs designed to treat different types of cancer, and each targeted therapy plan is tailored to a patient’s specific cancer and treatment goals. Each drug has different dosage requirements and can cause different side effects.

What you can expect from targeted therapy can vary widely based on many factors, including the type of medication prescribed, your overall health, and whether your targeted therapy is part of a plan that contains other treatments, such as radiation therapy or surgery. If targeted therapy is part of your treatment plan, your care team will talk with you about your selections and what to expect.

If you choose to administer your own targeted therapy medications, discuss safety protocols for handling medications with your physician. If infusion or injection is the recommended option, your care crew will tell you when and where to go and how long the treatments will take.

Before targeted therapy

Some targeted therapies, especially checkpoint inhibitors, must be given by infusion, which can take several hours. You may want to prepare for an extended visit to the hospital, outpatient center, or infusion site.

  • Get comfortable: Wear loose clothing to allow access to your port or catheter. Consider bringing a blanket or pillow.
  • Bring a friend: Consider bringing a friend or family member to keep you company and drive you to and from your appointment.
  • Stay busy: bring a tablet or book to read or watch a show during your session.
  • Bring a snack: Make sure you have some water and a light snack during your session.

After targeted therapy

Expect to follow up with your medical oncologist or other members of your care team throughout and after your embattled therapy regimen.

  • Manage side effects: Contact your care team if you are concerned about developing side effects or if they become serious.
  • Stay hydrated: Make sure you eat a healthy diet and drink plenty of fluids while attractive targeted therapy medications.